Disease mechanism: Unravelling Wiskott–Aldrich syndrome
نویسندگان
چکیده
The gene responsible for Wiskott-Aldrich syndrome, a disease affecting platelets and lymphocytes, has been cloned and its protein product (WASp) found to interact with the GTPase Cdc42. WASp seems to provide a link between Cdc42 and the actin cytoskeleton, perhaps explaining the cellular defects underlying the disease.
منابع مشابه
Wiskott-Aldrich Syndrome (WAS): A Case Report in Mauritius and Review
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ورودعنوان ژورنال:
- Current Biology
دوره 6 شماره
صفحات -
تاریخ انتشار 1996